How the current west african ebola virus disease epidemic is altering views on the need for vaccines and is galvanizing a global effort to field-test leading candidate vaccines
Levine MM., Tapia M., Hill AV., Sow SO.
The Ebola epidemic spreading in 3 of the world's least developed countries in West Africa, with high case-fatality rates and with health workers accounting for approximately 10% of the deaths, is a public health crisis that may be a harbinger of similar epidemics occurring wherever poverty is extreme, civil society is in turmoil, and health services are rudimentary. Since delivery of single-dose Ebola vaccines may serve as a future adjunct control measure, clinical trials of promising vaccines are commencing in Africa.